Mohamed Bouheroum
University of Freres Mentouri Constantine, Algeria
Title: The cytotoxicity effect of two saponins from Gymnocarpos decander species on Hela cells
Biography
Biography: Mohamed Bouheroum
Abstract
The modern pharmaceutical industry relies mainly on the diversity of plant secondary metabolites to find new molecules with novel biological properties; in this perspective, our objectives are the inventory as well as the chemical and pharmacological evaluation of Algerian species, in order to valorize and rationalize their traditional uses and to isolate compounds of potential therapeutic interest. n-butanol and ethyl acetate extracts of Gymnocarpos decander (Caryophyllaceae) were able to isolate five new products including two saponins and three flavonols glycosides, with three known products. The extract obtained undergoes chromatographic and spectroscopic investigations in order to isolate and establish the structures of the molecules that compose them by using various spectroscopic experiments (UV, 1D NMR and 2D and SM).