Ibrahim Elsayed
Gulf Medical University, UAE
Title: Design of Pharmaceutical Experiments Using Design Expert® Software
Biography
Biography: Ibrahim Elsayed
Abstract
The seminar gives an introduction to Design Expert® software to enable the audience to start using it. This software is a professional statistical tool used to create the experimental design, study the effects of different factors with the least possible number of trials and optimize the designed process through simultaneous selection of the desired level of each independent variable. Different statistical plans can be utilized as full factorial, response surface and mixture designs. The response surface is the most commonly used design in pharmaceutical research and it includes different sub-designs; e.g. central composite and Box-Behnken. Before starting the experimental part, the studied factors and traced responses are loaded into the Design Expert® software to determine the number and compositions/conditions of the experimental trials. After finishing the experimental work, the obtained data are fed into the software to assign different desirability values to the conducted experimental trials. Consequently, we can select the optimum trial having the maximum desirability value to be subjected to further investigations.