Maha AlMolaiki
King Saud University, Saudi Arabia
Title: Association between proton pump inhibitors use and new onset of ischemic stroke in a tertiary hospital, king Abdul-Aziz medical city-central region Saudi Arabia: Retrospective study
Biography
Biography: Maha AlMolaiki
Abstract
Aim: to assess the likelihood of developing new-onset ischemic stroke among patients who were using PPIs for 6 months or more versus patients who were not using PPIs.
Background: Stroke is a rapid loss of brain function due to disruption of blood supply to the brain and a major cause of mortality and morbidity worldwide. In Saudi Arabia, the incidence of ischemic strokes is 69%. The established risk factors are hypertension, diabetes mellitus, smoking, dyslipidemia. Proton pump inhibitors (PPIs) one of the world’s most frequently prescribed medications contributed to many adverse effects. In 2016, a retrospective study found a significant increase in the risk of new onset ischemic stroke in the PPIs users. In 2018, a prospective cohort study found no association.