Suad Yousif Abdalla Alkarib
University of Karary, Sudan
Title: Gum arabic acacia for manufacturing of tablet & pellets coating materials
Biography
Biography: Suad Yousif Abdalla Alkarib
Abstract
Introduction: Gum arabic is a complex, loose aggregate of sugars and hemicelluloses composed of arabic acid nucleus connected with calcium, magnesium, potassium and sugars arabinose, galactose, and rhamnose. In this study, the use of gum arabic acacia in the manufacturing of tablet coating material, using water and plasticizer to add elasticity and flexibility is detailed. Methodology: The study was performed using a solution of gum arabic acacia in a concentration (10%), using a pilot small coating machine with an inlet temperature 400C, and spraying rate 10ml every 5 minutes on the top of placebo tablet bed while continuous drying. The ratio of gum: water and plasticizer plays good roles in final coat characteristic. Physical tests were done for the tablets before and after the process. Results: The final placebo products after coating, should be inspected and tested for appearance and performance inspection should include checks for color, size, appearance, and any physical deficits in the coating, which could affect the performance or/and stability of the product. Conclusion: However, the effect of such variables water: plasticizer ratio gives different profiles with different physical characteristics. This study concludes optimized and stable coating formula from gum arabic. The use of colors and anti-transparency additives is highly required for both film and enteric coat, for technological identification, and according to customers reeds.