Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 12th Annual
Pharma Middle East Congress Dubai, UAE.

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Day 1 :

Pharma Middle East 2017 International Conference Keynote Speaker G Raid Alany photo
Biography:

Professor Raid Alany has over 25 years of international experience in pharmacy education, pharmaceutics and drug delivery research. His academic journey spans three continents, namely, Asia, Oceania and Europe. He received his PhD in drug delivery from the University of Otago, Dunedin New Zealand in 2001; was appointed as a Lecturer at the School of Pharmacy, The University of Auckland, Auckland, New Zealand, in 2001 where he was responsible for establishing the first pharmaceutics curriculum at The University of Auckland. He was promoted to a Senior Lecturer in 2004, appointed as Head of Pharmaceutics in 2007, promoted to Senior Lecturer above the bar in February 2009; appointed as Honorary Associate Professor in 2011. He joined Kingston University London as Professor (Chair) of Pharmaceutics in January 2011 and was appointed as Research Director for the School of Pharmacy and Chemistry in December 2013. He has been appointed as the Inaugural Head of School of Life Sciences, Pharmacy and Chemistry on 1st of June 2015. Raid won several awards such as Microscopy New Zealand Young Scientists Award in 1999 The University of Auckland's Vice Chancellor's Early Career Research Excellence Award in 2003, the Controlled Release Society Veterinary Programme co-chair/ chair Distinguished Service Awards in 2008/2009 and the Spark Ideas Challenge, Uniservices Prize and Chiasma Prize in 2011. He consults for human and veterinary pharmaceutical companies in New Zealand and Singapore and is an inventor on several international patents.

Abstract:

TBS

  • Sessions:
    Clinical Pharmacy and Pharmacotherapeutics | Industrial Pharmacy and Pharmacy Practice | Drugs and Regulations
Speaker
Biography:

 

Bayan Darwesh has completed her pharm D from King Abdulaziz  University in Jeddah. She is  director of Pharmacy Department in King Abdulaziz University Hospital in Jeddah. She is responsible to Initiate Pharmacy Automation projects to streamline and modernize the daily routine workflow in line with international standards.

 

Abstract:

 

The use of automated dispensing systems has been lauded for improving patient safety within the processes of healthcare. Adverse drug events, for example, are a common manifestation of faults in the service delivery of a pharmacy department that endanger patient safety. Even though automation may reduce the occurrence of such errors, concerns have been raised about the efficiency and safety of the automated systems since a large number of patients still suffer medication associated injuries. Though the use of these systems is common in some developed countries, there is paucity of safety and efficacy data from the Arab nations. We therefore report our experience using automated dispensing systems in all our units at the KAUH following a successful pilot run of this technology. 

Materials and methods: We installed the automated dispensing system and monitored the number of controlled and uncontrolled medications used before and after the automation, the incidence of wrong bin opening and the number of IV medication preparations after the installation of the system.

Results: The number of controlled and uncontrolled medications dispensed in KAUH generally reduced. The decrease in the number of uncontrolled medication was statistically significant, p value 0.004. We also observed an increase in the number of IV medication preparations consequent to reduced workload and improvement in staff utilization. After installation of the automated dispensing system there was a high incidence of wrong bin opening, which reduced gradually after the first two months. 

Speaker
Biography:

Saeed Albaraki completed his PhD from University of Leeds, UK in 2011 in industrial pharmacy and pharmaceutical engineering.  Dr. Albaraki is the Deputy Director of the Scientific Research Centre of the Medical Services of the Armed Forces, KSA. He has published his research work on pharmaceutical formulation, manufacturing, plasma fractionation and pharmaceutical engineering in reputed journals and has also presented his work in national and international scientific conferences and meetings.

Abstract:

Technically, human plasma for fractionation may be obtained by separation of plasma from whole blood (recovered plasma) or by apheresis (source plasma). The use of Apheresis technique is very helpful in the recovery of plasma and yields almost four times more than other techniques. The bulk of the plasma collected for fractionation is provided by paid donors. For example, USA plasma derived yield from whole blood amounted to 3.5 million litres, while 12 million litres was obtained via plasmapheresis. As with other pharmaceutical industries, PDM fractionation investment is based on four aspects, Knowhow, market, high capital and raw material (Plasma). The main obstacle to start local plasma fractionation is the maintenance of a regular, adequate and safe source of supply of around 300K litres of   plasma. In case of shortage of plasma supplies, the alternative project such as self-sufficiency program (SSP) need to be implemented. Finland, Malaysia, Norway and Singapore are good example of self-sufficiency fractionation toll of local plasma. SSP based on local collection of plasma (around 30k-50k litres ) and shifting fractionation through special contracts with international fractionators. Consumption of PDM products such coagulation factors FVIII and FIX, albumin and immunoglobulins (IVIG) shows around 10% annual increment. The recent applications of IVIG in  Alzheimer’s disease  and some other  neurological disorders has created a profound interest and use of PDM products. Unlike pharmaceutical industry, around 40% of the final price for the manufacturing of PDM  goes to raw materials and not to marketing. Collection of local plasma for fractionation will dramatically reduce the final prices of the products. In addition, building up a national  collection program of plasma will increase the local strategic stock for any crisis. The fractionated yield of coagulation factors produced by Self-sufficiency fractionation program is very high and will greatly  help to start a prophylaxis program for haemophilic patients. Local fractionation or SSP will also help in the creation of the much needed  local employment opportunities and support the local economy. SSP will also  help to secure a reglar , uninterrupted  and safe supply for the patients receiving PDM . A better quality control can also be implemented to strenghten the safety standards of the final products and the influence of any possible gene therapy will be excluded.

Biography:

Abstract:

Inhaled-medication delivered during mechanical-ventilation is affected by type of aerosol-generator and humidity-condition. Despite many in-vitro studies related to aerosol-delivery to mechanically-ventilated patients, little has been reported on clinical effects of these variables.The aim of this study was to determine effect of humidification and type of aerosolgenerator on clinical-status of mechanically-ventilated asthmatics.72 (36-females) asthmatic-subjects receiving invasive-mechanical-ventilation were enrolled and assigned randomly to 6-treatment groups of 12 (6-females) subjects each received, as possible, all inhaled-medication using their assigned aerosol-generator and humidity-condition during delivery. Aerosol-generators were placed immediately after humidifier within inspiratory-limb of mechanical-ventilation-circuit. First-group used vibrating-mesh-nebulizer (Aerogen-Solo; VM) with-humidification; Second used VM without-humidification; Third used metered-dose-inhaler with AeroChamber-Vent (MDI-AV) with-humidification; Forth used MDI-AV withouthumidification; Fifth used Oxycare-jet-nebulizer (JN) with-humidification; Sixth used JN without-humidification. Measured parameters included clinical-parameters reflected asthma-severity (CP) and end-point-parameters e.g. length-of-stay in the intensive-care-unit (ICU-days) and mechanical-ventilation-days (MV-days).
There was no significant difference between studied subjects in the 6-groups in
baseline of CP. VM resulted in trend to shorter ICU-days (~1.42days) compared to MDI-AV (p=0.39) and relatively but not significantly shorter ICU-days (~0.75days) compared JN. Aerosol delivery with or without-humidification did not have any significant effect on any of parameters studied with very light insignificant tendency of delivery at humidcondition to decrease MV-days and ICU-days. No significant effect was found of changing humidity during aerosol-delivery to ventilated-patient. VM to deliver aerosol in ventilated-patient resulted in trend to decreased ICU-days compared to JN and MDI-AV. However, we recommend increasing the number of patients studied to corroborate this finding.

Biography:

Idin Alikhani, 3rd year pharmacy student of  Kermanshah University of Medical Sciences, Kermanshah, Iran

Abstract:

Introduction and Background: The impacts of self-medication on the health care costs and patients safety are very significant. Therefore, realizing drugs that is being requested more frequent by people from pharmacies can help finding a reasonable and rational solution to this problem. All around the world, it is evaluated that half of all medicines are prescribed, dispensed or sold inappropriately, and half of all patients do not take their drugs properly. Inappropriate use of drugs is costly and extremely detrimental for both individual and society.

Methods: In this descriptive cross-sectional study, 100 pharmacies (More than 80% of established pharmacies in Kermanshah) filled a 10-item researcher made questionnaire. Data were analyzed using analytic statistical programs.

Results: Results showed that the following drugs had most frequency in patients’ requests: Cap Amoxicillin 500 mg (85.7%), Cap Gelofen® 400 mg (84.4%), Tab Acetaminophen codeine (76.6%), Tab Adult cold (75.3%), Tab Ranitidine (67.5%), Amp Dexamethasone (61.0%), Syr Diphenhydramine compound (53.2%), Vial penicillin 6.3.3 (44.1%), Tab Alprazolam 1 mg (36.3%), cap Novafen® (26.5%)

Discussion and Conclusion: The most important reason of self-medication could be due to 1- Self-awareness assumption about medical and pharmaceutical issues 2- Consumption of mentioned drugs in non-serious illnesses such as common cold, headache, gastrointestinal diseases and sleep disorders 3- Frequent suffering disorders which lead to take medicine, 4- Physician’s crowded office 5- High cost of medical care services, low income and social poverty.

 

Biography:

Abstract:

The strategy of price liberalisation and privatisation had been implemented in Sudan over the last decade, and has had a positive result on government deficit. The investment law approved recently has good statements and rules on the above strategy in particular to pharmacy regulations. Under the pressure of the new privatisation policy, the government introduced radical changes in the pharmacy regulations. To improve the effectiveness of the public pharmacy, resources should be switched towards areas of need, reducing inequalities and promoting better health conditions. Medicines are financed either through cost sharing or full private. The role of the private services is significant. A review of reform of financing medicines in Sudan is given in this study. Also, it highlights the current drug supply system in the public sector, which is currently responsibility of the Central Medical Supplies Public Corporation (CMS). In Sudan, the researchers did not identify any rigorous evaluations or quantitative studies about the impact of drug regulations on the quality of medicines and how to protect public health against counterfeit or low quality medicines, although it is practically possible. However, the regulations must be continually evaluated to ensure the public health is protected against by marketing high quality medicines rather than commercial interests, and the drug companies are held accountable for their conduct.

Speaker
Biography:

Dr. Krishna Murti has completed  PhD in Pharmaceutical Sciences and has more than 15 years of Experience in academic as well as industry both national and international.His area of interest is diabetes ,cancer and wound healing .Presently ,He is working as Faculty in Department of Pharmacy Practice in NIPER ,Hajipur, institute of National Importance ,established by Government of India. He has published more than 80 papers in reputed journals and has been serving as an editorial board member of reputed journals. He is member of several Pharmaceutical bodies. 

Abstract:

Objectives: Comparative effect of fixed dose combination of Telmisartan+Amlodipine versus Telmisartan and Amlodipine alone on Brain Natriuretic Peptide (BNP), Cystatin - C and blood pressure in essential hypertensive patients.

Methods: A total of 90 patients, fulfilling inclusion and exclusion criteria were enrolled in the study after obtaining informed consent. Patients were randomized into three treatment groups i.e. Telmisartan 40 mg (Group A), Amlodipine 5 mg (Group B)  and low fixed dose combination of Telmisartan 40 mg +Amlodipine 5 mg (Group C) once daily for three  months. The systolic BP, Diastolic BP, BNP, Cystatin C were recorded at the start of the study and end of the study.              

Results: In the present study, significant reduction of mean systolic blood pressure (SBP) and mean diastolic blood pressure (DBP), BNP & Cystatin - C was seen in low fixed dose combination of Amlodipine 5 mg and Telmisartan 40 mg (Group C) compared to Telmisartan 40 mg and Amlodipine 5 mg mono-therapy. Some of adverse drug reactions (ADRs) were reported in Amlodipine mono-therapy group, like ankle oedema, headache, constipation and fatigue.

Discussion and Conclusion: Low fixed dose combination therapy appears to be a better therapeutic approach in relation of BP, BNP and Cystatin-C control than mono-therapy for primary hypertensive patients.

Speaker
Biography:

Prof. M Al-Arifi. Has graduated with Bsc in pharmacy from College of Pharmacy, King Saud University, 1986, and finished his PhD, in clinical pharmacy, from School of pharmacy, Queens' University of Belfast, 1993, since then and up till now in the clinical pharmacy department, college of pharmacy King Saud University. Has engaged in teaching and supervising graduate and undergraduate students and published more than fifty articles for the last twenty years.

 

Abstract:

The study was conducted during the period from May 2006 to September 2006 in Riyadh city. The survey composed of the demographic characteristics of the respondents, asked 6 Likert type questions about the attitudes of the pharmacists toward mental illness,   providing pharmaceutical care to mentally ill patients, the barriers of the provision the service and differentiated between different types of mental illness and compares them with cardiovascular medications.  Although pharmacists have generally positive attitudes toward both mental illness and providing pharmaceutical care to mentally ill patients, they felt uncomfortable counseling or follow-up monitoring patients for adverse drug-related problems when consider distinguishing between different types of mental illness.

Speaker
Biography:

Rahul Kumar is presently pursuing PhD in Pharmacy Practice in National Institute of Pharmaceutical Education & Research ,Hajipur ,an institute of national importance established by Government of India . He has comleted his Masters from NIPER,Hajipur and B.Pharm from  Manipal College of Pharmaceutical Sciences, (MCOPS) Manipal University, Manipal (both being premiere institutes of India.)He has qualified national level exams  for scholarships from AICTE and NIPER during masters as well as during  PhD . His research interest includes Clinical Pharmacy in Oncology ,Public Health and Environmental Health.

Abstract:

 Cervical cancer is the second most common gynecological malignancy worldwide. According to HPV Information Centre, Spain (Aug’ 2014), in India approximately 1,22,844 women are diagnosed with the disease every year and of them 67,477 die due to the disease. The etiology is multifactorial. Malondialdehyde (MDA) is important peroxide which is a measurement of oxidative stress and can be a predictive in the early detection of cervix cancer . This study has been undertaken to investigate the association of Arsenic and malondialdehyde (MDA) level with haematological changes at the first clinical presentation. Thiobarbituric Acid Reactive Substances (TBARS) assay was performed on the blood serum samples taken from the freshly diagnosed cervical cancer patients. For haematological changes, haematocytometer and Sahli’s method was followed. Mean MDA level in the serum of freshly diagnosed cervix cancer patients was found to be elevated than the healthy volunteers . Mean RBC count was found to be  comparatively less than the normal and mean WBC was found to be  comparatively higher than the normal. MDA may have a predictive role in treatment response. MDA levels are higher in patients of cervical cancer and suffer from haematological derangements. Arsenic is also one of the agents for causing Oxidative Stress. Arsenic is considered responsible for generation of free radicals and eventually for apoptosis. Arsenic estimation was performed with the help of Atomic Absorption Spectrometer (AAS). RBC count and Heamoglobin levels were performed according to standard protocol. MDA was in direct proportion with arsenic concentration and inversely proportional to RBC and Haemoglobin in CaCx  patients . Arsenic is one of the major causative agents for oxidative stress and hence may be a risk factor leading to cancer including CaCx.

Biography:

Abstract:

 

Background and objectives:  Rheumatoid Arthritis patient’s adherence to pharmacologic therapy is important to achieve therapeutic goals and improve outcomes. Our study objectives are to explore the adherence level, disability index and pain score in patients with rheumatoid arthritis and to understand the relationship between certain patient variables with adherence and Disability. Design and settings: A cross-sectional study with a self-administered questionnaire to RA patients. Participants gave their consent and were recruited from outpatient pharmacy waiting areas in different tertiary hospitals in Riyadh, the capital city of Saudi Arabia. Patients and Methods: This study Included (126) adults with Rheumatoid Arthritis. A self-administered questionnaire to RA patients using a special tool that collect demographic and clinical information, adherence and outcome assessment. 4 pages survey that contains three sections: (1) demographic and clinical data, (2) Adherence measured using 8-item Morisky Medication Adherence Scale (MMAS-8) by using validated Arabic version to assess patient's adherence, (3) Health Assessment Questionnaire (HAQ) to assess patient's outcomes. RESULTS: Scores of (MMAS-8items) ranging from 0 to 8 shows that approximately one-half the participants were (n=66) 52.3% non-adhered or show low adherence while (n=12) 9.5% of patients were adhered (high adherence), the remaining participants (n=48) shows 38% medium adherence. Those non-adhered almost (n=23) 18.2% of them shows low adherence after the first 5 years of diagnosis. About (n=35) 27.7% of none adhered had from 2-3 medications used for RA while those had more than three medications shows only (n=19) 15% low adherence. There were no significant differences between clinical and demographic variables between groups. CONCLUSIONS: The vast majority of RA patients have low to medium adherence score. Advanced age, years of diagnosis and number of medication significantly affect disability score. However, there is no relationship between these factors and pain score.

Biography:

Rachael Cheh graduated with a Bachelor of Pharmacy from the University of South Australia in 2008 and completed her Pharmacy Internship at the Repatriation General Hospital, South Australia. She worked as a Clinical Pharmacist at The Queen Elizabeth Hospital (TQEH) for a number of years in a variety of areas including the Emergency Department and Acute Medical Unit where she gained a variety of experiences. Subsequently she was the Specialist Clinical Pharmacist – Haematology/Oncology outpatients where she gained a deeper understanding and knowledge of the area.
Rachael is now Senior Pharmacist Medication Safety, Clinical and Formulary (TQEH, CALHN, SA Pharmacy). She has a keen interest in research, drug use management and progression of the pharmacy profession.

Abstract:

Background: Medication-related hospital admissions in Australia have previously been estimated to account for approximately 3% of all hospital admissions, with hospital entry points being a point of vulnerability. The timely medication review and reconciliation by a pharmacist at the early stage of an admission for patients admitted to the Acute Medical Unit (AMU) would be beneficial. Setting: The Emergency Department (ED) and AMU in a 300 bed tertiary teaching hospital, in South Australia. Objective: To investigate the impact of a Medical Admissions (MA) pharmacist on the proportion of AMU patients who receive a complete and accurate medication history by a pharmacist prior to admission and within 4 h of presentation. Method: This prospective observational study with a non-concurrent parallel study design examined a standard clinical pharmacist service within the AMU and ED to a Medical Admissions (MA) Pharmacist, in addition to the standard AMU and ED pharmacist service. Continuous variables were analysed using a two sample t test, whilst categorical data were analysed using Fisher’s exact test. Risk ratios were also calculated for categorical data, with p < 0.05 taken as statistically significant. Main outcome measures: Rates of completion of a complete medication history prior to admission and proportion of patients seen within 4 h of presentation by a pharmacist. Results: The intervention resulted in more patients receiving a complete medication history prior to admission (2.7% in the control group vs 18.5%, p < 0.01) and being seen by the pharmacist within 4 h of presentation (1.6% in the control group vs 7.5%, p < 0.01). Conclusion: Implementation of an extended hours clinical pharmacy service in the form of a medical admissions pharmacist based in the ED significantly increased the number of complete medication histories and clinical reviews completed for patients being admitted to an AMU. These were also completed earlier in the patients’ admission. There was also a small trend toward increasing the proportion of patients discharged by 11 am in the intervention group.

Speaker
Biography:

In the future urgent, acute and emergency medicine clinical workforce, new models of care and care delivery need to be developed, in order to maintain and enhance standards of safe and accessible patient care. A departure from traditional (doctor-led) approaches to workforce planning and an understanding of the scope and governance surrounding emerging clinical roles is necessary to develop a sustainable, multi-skilled workforce across primary, community and secondary care. Today’s healthcare workforce includes an ever-increasing number of non-doctor professionals, undertaking clinical work in the medical domain. The traditional, medicines-focused role of the pharmacist is being challenged by NHS Health Education England (HEE) - the organisation responsible for NHS workforce training and development in England - and its national stakeholders.

It is contended that the future pharmacist clinician should be able to confidently and competently manage patients at an advanced clinical level – with health assessment, diagnostics and clinical examination skills comparable with that of a mid-level clinician. A recent three-year programme undertaken by HEE, evaluated the potential for pharmacists to manage patients in the emergency department and across urgent and acute care in England. Evidence from the ‘Pharmacists in Emergency Departments’ (PIED) suite of studies suggests that pharmacists with advanced training may clinically manage up to 36% of patients attending emergency departments. The HEE programme examines this data and proposes enhanced clinical development pathways for pharmacists. The programme team propose a change in thinking around the deployment of pharmacists in the future integrated clinical workforce across urgent, acute and emergency care.

Abstract:

In the future urgent, acute and emergency medicine clinical workforce, new models of care and care delivery need to be developed, in order to maintain and enhance standards of safe and accessible patient care. A departure from traditional (doctor-led) approaches to workforce planning and an understanding of the scope and governance surrounding emerging clinical roles is necessary to develop a sustainable, multi-skilled workforce across primary, community and secondary care. Today’s healthcare workforce includes an ever-increasing number of non-doctor professionals, undertaking clinical work in the medical domain. The traditional, medicines-focused role of the pharmacist is being challenged by NHS Health Education England (HEE) - the organisation responsible for NHS workforce training and development in England - and its national stakeholders.

It is contended that the future pharmacist clinician should be able to confidently and competently manage patients at an advanced clinical level – with health assessment, diagnostics and clinical examination skills comparable with that of a mid-level clinician. A recent three-year programme undertaken by HEE, evaluated the potential for pharmacists to manage patients in the emergency department and across urgent and acute care in England. Evidence from the ‘Pharmacists in Emergency Departments’ (PIED) suite of studies suggests that pharmacists with advanced training may clinically manage up to 36% of patients attending emergency departments. The HEE programme examines this data and proposes enhanced clinical development pathways for pharmacists. The programme team propose a change in thinking around the deployment of pharmacists in the future integrated clinical workforce across urgent, acute and emergency care.

Speaker
Biography:

Fadhila Helnisa has completed her bachelor degree from Faculty of Pharmacy on 2014, Andalas University (Indonesia) and has successfully fulfilled all the academic requirements of Indonesian Pharmacist Profession on 2015. Now, she is studying at Master of Toxicology, University of Birmingham.

Abstract:

A study on clinical pharmacokinetics aspect of drugs in patients with hypertension at the Internal Medicine Department of Hospital Padang Panjang (Indonesia) has been conducted. The aims of the research was to determine the accuracy of antihypertensive medications to achieve targeted blood pressure and to assess the dosage regimen based on liver and/or kidney functions, also drug interactions. The study was performed from December 2013 to February 2014. This is observational prospective study with 49 patients who met the inclusion and exclusion criteria. Data was analyzed descriptively. Results showed that 60.42% antihypertensive medications were effective but 39.58% not effective to reach the targeted blood pressure. There were 3 cases in appropriate dose regimen covering 1 case digoxin, 1 case furosemid and 1 case captopril. From the cases, doses exceed individual dose included digoxin and captopril.  There were 14 cases of pharmacokinetic interactions and 2 cases of pharmacodynamic interactions. Interaction between amlodipine and diltiazem (7 patients, 14.58%) influenced the blood pressure control in patient. These are pharmacokinetic interaction because diltiazem decreases metabolism of amlodipine by inhibiting enzyme CYP 3A3/4.