Preformulation Studies and Techniques

Preformulation studies are important elements to be considered during the process of drug development research to support development of formulations at different phases of clinical trials. As from the word preformulation the activities that are done before formulation development are called as preformulation studies. It gives the scientific basis for formulation development. This session is concentrated on topics like solubility, dissociation constant, salt formation, partition or distribution coefficient, pH, polymorphism, solubility profile and dissolution kinetics etc.

  • Material characterisation - chemical and physical
  • Morphic form identification
  • Salt selection
  • Compressibility testing
  • Excipient and Process compatibility testing and etc.

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